Approximately 200 enzymes require NAD or NADP+. We will go through some selected functions of NAD and NADP+. The following figures and legends show and describe the functions of NAD and NADP+.
HMG CoA reductase, the rate-limiting enzyme in cholesterol synthesis, uses NADPH. NADPH is also used by the antioxidant enzyme glutathione reductase as shown in the link below6.
Web Link
–The Glutathione Oxidation Reduction (Redox) Cycle |
References & Links
1. http://en.wikipedia.org/wiki/File:CellRespiration.svg
2. http://en.wikipedia.org/wiki/File:Citric_acid_cycle_with_aconitate_2.svg
3. http://en.wikipedia.org/wiki/File:Ethanol_flat_structure.png
4. https://en.wikipedia.org/wiki/Acetaldehyde#/media/File:Acetaldehyde-2D-flat.svg
5. http://en.wikipedia.org/wiki/Mitochondrion
6. Gropper SS, Smith JL, Groff JL. (2008) Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Publishing.
Links