{"id":1026,"date":"2017-10-27T16:42:44","date_gmt":"2017-10-27T16:42:44","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/?post_type=chapter&p=1026"},"modified":"2017-11-14T17:44:33","modified_gmt":"2017-11-14T17:44:33","slug":"12-73-iron-functions","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/atd-herkimer-nutrition\/chapter\/12-73-iron-functions\/","title":{"raw":"12.73 Iron Functions","rendered":"12.73 Iron Functions"},"content":{"raw":"
\r\n\r\nAs we talked about in the previous subsection, there are 3 primary functional iron subcompartments.\r\n\r\n1. Hemoglobin\r\n\r\n2. Myoglobin\r\n\r\n3. Iron-containing enzymes\r\n\r\nHemoglobin contains heme that is responsible for red blood cells\u2019 red color. Hemoglobin carries oxygen to tissues. The function of hemoglobin can be seen in the link below.\r\n<\/colgroup>\r\n\r\n\r\n
Web Link<\/b>\r\n\r\n-Hemoglobin<\/u><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\nMyoglobin is similar to hemoglobin in that it can bind oxygen. However, instead of being found in blood, it is found in muscle. The color of meat products is a result of the state that myoglobin is in, as shown in the link below.\r\n<\/colgroup>\r\n\r\n\r\n
Web Link<\/b>\r\n\r\n-Myoglobin & Meat Color<\/u><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\nThere are a number of enzymes that use iron as a cofactor. We've already talked about two in this class.\r\n\r\nIron is a cofactor for the antioxidant enzyme, catalase, that converts hydrogen peroxide to water, as shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"1139\"]\"\" Figure 12.731 Catalase uses iron as a cofactor[\/caption]\r\n\r\n<\/div>\r\nIron is also a cofactor for proline and lysyl hydroxylases that are important in collagen cross-linking. This will be discussed further in the vitamin C section. The function of these enzymes is shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"865\"]\"\" Figure 12.732 Importance of ascorbic acid and iron to proline and lysyl hydroxylases.[\/caption]\r\n\r\n<\/div>\r\nHeme iron is also found in cytochromes, like cytochrome c in the electron transport chain as shown below1<\/sup>.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"945\"]\"\" Figure 12.733 Cytochrome c in the electron transport chain contains\u00a0iron<\/span>2<\/sup>[\/caption]\r\n\r\n<\/div>\r\nReferences & Links<\/b>\r\n\r\n1. Gropper SS, Smith JL, Groff JL. (2008) Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Publishing.\r\n\r\n2. http:\/\/wikidoc.org\/index.php\/File:ETC.PNG\r\n\r\nLinks<\/b>\r\n\r\nHemoglobin - http:\/\/www.nlm.nih.gov\/medlineplus\/ency\/imagepages\/19510.htm\r\n\r\nMyoglobin & Meat Color - http:\/\/meatisneat.files.wordpress.com\/2009\/09\/slide11.jpg\r\n\r\n<\/div>","rendered":"
\n

As we talked about in the previous subsection, there are 3 primary functional iron subcompartments.<\/p>\n

1. Hemoglobin<\/p>\n

2. Myoglobin<\/p>\n

3. Iron-containing enzymes<\/p>\n

Hemoglobin contains heme that is responsible for red blood cells\u2019 red color. Hemoglobin carries oxygen to tissues. The function of hemoglobin can be seen in the link below.<\/p>\n\n\n<\/colgroup>\n\n\n
Web Link<\/b><\/p>\n

–Hemoglobin<\/u><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Myoglobin is similar to hemoglobin in that it can bind oxygen. However, instead of being found in blood, it is found in muscle. The color of meat products is a result of the state that myoglobin is in, as shown in the link below.<\/p>\n\n\n<\/colgroup>\n\n\n
Web Link<\/b><\/p>\n

–Myoglobin & Meat Color<\/u><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

There are a number of enzymes that use iron as a cofactor. We’ve already talked about two in this class.<\/p>\n

Iron is a cofactor for the antioxidant enzyme, catalase, that converts hydrogen peroxide to water, as shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 12.731 Catalase uses iron as a cofactor<\/p>\n<\/div>\n<\/div>\n

Iron is also a cofactor for proline and lysyl hydroxylases that are important in collagen cross-linking. This will be discussed further in the vitamin C section. The function of these enzymes is shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 12.732 Importance of ascorbic acid and iron to proline and lysyl hydroxylases.<\/p>\n<\/div>\n<\/div>\n

Heme iron is also found in cytochromes, like cytochrome c in the electron transport chain as shown below1<\/sup>.<\/p>\n

\n
\"\"<\/p>\n

Figure 12.733 Cytochrome c in the electron transport chain contains\u00a0iron<\/span>2<\/sup><\/p>\n<\/div>\n<\/div>\n

References & Links<\/b><\/p>\n

1. Gropper SS, Smith JL, Groff JL. (2008) Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Publishing.<\/p>\n

2. http:\/\/wikidoc.org\/index.php\/File:ETC.PNG<\/p>\n

Links<\/b><\/p>\n

Hemoglobin – http:\/\/www.nlm.nih.gov\/medlineplus\/ency\/imagepages\/19510.htm<\/p>\n

Myoglobin & Meat Color – http:\/\/meatisneat.files.wordpress.com\/2009\/09\/slide11.jpg<\/p>\n<\/div>\n\n\t\t\t

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Candela Citations<\/h3>\n\t\t\t\t\t
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