{"id":669,"date":"2017-10-26T15:40:36","date_gmt":"2017-10-26T15:40:36","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/sunynutrition\/?post_type=chapter&p=669"},"modified":"2017-11-14T15:22:25","modified_gmt":"2017-11-14T15:22:25","slug":"9-24-vitamin-e-deficiency-toxicity","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/atd-herkimer-nutrition\/chapter\/9-24-vitamin-e-deficiency-toxicity\/","title":{"raw":"9.24 Vitamin E Deficiency & Toxicity","rendered":"9.24 Vitamin E Deficiency & Toxicity"},"content":{"raw":"
\r\n\r\nVitamin E deficiency is extremely rare. Depletion studies require years on a vitamin E-deficient diet to cause deficiency1<\/sup>. Deficiency primarily occurs in people with lipid malabsorption problems or Ataxia with Isolated Vitamin E Deficiency (AVED). Individuals with AVED have a mutation in their alpha-TTP that prevents it from functioning correctly. The primary symptoms of vitamin E deficiency are neurological problems.\r\n\r\nHigh levels of vitamin E intake do not result in a noted toxicity. However, higher levels of intake are associated with decreased blood coagulation. In particular, hemorrhagic stroke has been linked to high vitamin E levels. The link below shows that in this condition a blood vessel ruptures or leaks in the brain.\r\n<\/colgroup>\r\n\r\n\r\n
Web Link<\/b>\r\n\r\nHemorrhagic Stroke<\/u><\/a>-<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\nIt is believed that this increased bleeding risk is due to a vitamin E metabolite that has anti-vitamin K activity. This potential antagonism will be described more in the vitamin K section.\r\n\r\nReferences & Links<\/b>\r\n\r\n1. DRI (2000) Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids.\r\n\r\nLink<\/b>\r\n\r\nHemorrhagic Stroke - http:\/\/heart.arizona.edu\/heart-health\/preventing-stroke\/lowering-risks-stroke\r\n\r\n<\/div>","rendered":"
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Vitamin E deficiency is extremely rare. Depletion studies require years on a vitamin E-deficient diet to cause deficiency1<\/sup>. Deficiency primarily occurs in people with lipid malabsorption problems or Ataxia with Isolated Vitamin E Deficiency (AVED). Individuals with AVED have a mutation in their alpha-TTP that prevents it from functioning correctly. The primary symptoms of vitamin E deficiency are neurological problems.<\/p>\n

High levels of vitamin E intake do not result in a noted toxicity. However, higher levels of intake are associated with decreased blood coagulation. In particular, hemorrhagic stroke has been linked to high vitamin E levels. The link below shows that in this condition a blood vessel ruptures or leaks in the brain.<\/p>\n\n\n<\/colgroup>\n\n\n
Web Link<\/b><\/p>\n

Hemorrhagic Stroke<\/u><\/a>–<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

It is believed that this increased bleeding risk is due to a vitamin E metabolite that has anti-vitamin K activity. This potential antagonism will be described more in the vitamin K section.<\/p>\n

References & Links<\/b><\/p>\n

1. DRI (2000) Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids.<\/p>\n

Link<\/b><\/p>\n

Hemorrhagic Stroke – http:\/\/heart.arizona.edu\/heart-health\/preventing-stroke\/lowering-risks-stroke<\/p>\n<\/div>\n\n\t\t\t

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Candela Citations<\/h3>\n\t\t\t\t\t
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