Objective: Solve problems involving heritable conditions related to chromosomal inheritance.
Use this page to check your understanding of the content.
- Sex chromosomes
Study Guide Questions
- Be able to read and interpret any karyotype, including determining the chromosomal gender of the “patient”.
- Successfully solve heredity problems involving sex-linked characteristics.
- Example: Hemophilia in humans is a condition resulting in a failure to form blood clots, resulting in excessive bleeding. It is due to a mutation in a gene found on the X-chromosome. What possible offspring can result from a baby-making union between a non-carrier female and a hemophilac male?
- For more practice, visit: http://www.biology.arizona.edu/mendelian_genetics/problem_sets/sex_linked_inheritance/sex_linked_inheritance.html
- When given an example of aneuploidy, be able to hypothesize how it occurred. (Did non-disjunction take place during meiosis I or meiosis II? How can you tell? Can you always tell?)
- Be able to read and interpret pedigrees.
- In this pedigree, the shaded individuals are homozygous recessive. What is the genotype of individual B?
- What is the genotype of individual E?
- If E married an individual who is homozygous recessive, what is the probability that their first child will be homozygous recessive?
- For practice, see: http://bio3400.nicerweb.com/med/QUIZ/pedigree_q.html
- Why are pedigrees necessary when studying human inheritance patterns?