Biology of Emotion
The limbic system, autonomic nervous system, and reticular activating system interact in the processing of emotion.
Explain the physiology of emotional response in terms of the structures and systems involved
- The limbic system, autonomic nervous system, and reticular activating system all interact in the physiological processing of emotion.
- The limbic system categorizes human emotional experiences as either pleasant or unpleasant mental states. Neurochemicals such as dopamine, noradrenaline, and serotonin are important components of the limbic system.
- The autonomic nervous system, together with the hypothalamus, regulates pulse, blood pressure, breathing, and arousal in response to emotional cues.
- When activated, the sympathetic nervous system prepares the body for emergency actions by controlling the glands of the endocrine system. Conversely, the parasympathetic nervous system functions when the body is relaxed or at rest and helps the body store energy for future use.
- The reticular activating system is believed to first arouse the cortex and then maintain its wakefulness so that sensory information and emotion can be interpreted more effectively.
- homeostasis: Equilibrium of the body, in which biological conditions (such as body temperature) are maintained at optimal levels.
- cerebral cortex: The grey, folded, outermost layer of the cerebrum that is responsible for higher brain processes such as sensation, voluntary muscle movement, thought, reasoning, and memory.
- amygdala: A part of the brain located in the medial temporal lobe. It is believed to play a key role in emotion in both animals and humans, particularly in the formation of fear-based memories.
- hippocampus: A part of the limbic system, located in the temporal lobe of the brain and consisting mainly of grey matter. It plays a role in memory and emotion.
- emotion: The complex psychophysiological experience of an individual’s state of mind as it is interacting with biochemical (internal) and environmental (external) influences.
Emotions can be explained in biological and neurological terms. The limbic system, autonomic nervous system, and reticular activating system all interact to assist the body in experiencing and processing emotions.
The Limbic System
The limbic system is the area of the brain most heavily implicated in emotion and memory. Its structures include the hypothalamus, thalamus, amygdala, and hippocampus. The hypothalamus plays a role in the activation of the sympathetic nervous system, which is a part of any emotional reaction. The thalamus serves as a sensory relay center; its neurons project signals to both the amygdala and the higher cortical regions for further processing. The amygdala plays a role in processing emotional information and sending that information on to cortical structures. The hippocampus integrates emotional experience with cognition.
Other parts of the limbic system include the olfactory bulbs, anterior nuclei, fornix, column of fornix, mammillary body, septum pellucidum, habenular commissure, cingulate gyrus, parahippocampal gyrus, limbic cortex, and limbic midbrain areas.
The processes of the limbic system control our physical and emotional responses to environmental stimuli. This system categorizes the experience of an emotion as a pleasant or unpleasant mental state. Based on this categorization, neurochemicals such as dopamine, noradrenaline, and serotonin increase or decrease, causing the brain’s activity level to fluctuate and resulting in changes in body movement, gestures, and poses.
The amygdala, located in the left and right temporal lobes of the brain, has received a great deal of attention from researchers investigating the biological basis of emotions, particularly of fear and anxiety (Blackford & Pine, 2012; Goosens & Maren, 2002; Maren, Phan, & Liberzon, 2013). The amygdala plays a decisive role in the emotional evaluation and recognition of situations as well as in the analysis of potential threats. It handles external stimuli and induces vegetative reactions.
Two parts of the amygdala include the basolateral complex and the central nucleus. The basolateral complex has dense connections with a variety of sensory areas of the brain. It plays a critical role in classical conditioning and in attaching emotional value to learning processes and memories. The central nucleus plays a role in attention. It has connections with the hypothalamus and various areas of the brainstem and regulates the activity of the autonomic nervous and endocrine systems (Pessoa, 2010).
Research suggests that the amygdala is involved in mood and anxiety disorders. Changes in amygdala structure and function have been found in adolescents who either are at risk for or have been diagnosed with a mood or anxiety disorder (Miguel-Hidalgo, 2013; Qin et al., 2013). It has also been suggested that functional differences in the amygdala could be used to differentiate individuals suffering from bipolar disorder from those suffering from major depressive disorder (Fournier, Keener, Almeida, Kronhaus, & Phillips, 2013).
The hippocampus is also involved in emotional processing. As with the amygdala, research has demonstrated that hippocampal structure and function are linked to a variety of mood and anxiety disorders. Individuals suffering from posttraumatic stress disorder ( PTSD ) show marked reductions in volume in several parts of the hippocampus, which may be the result of decreased levels of neurogenesis and dendritic branching (the generation of new neurons and the generation of new dendrites in existing neurons, respectively) (Wang et al., 2010). While it is impossible to determine causation, studies have found improvements in behavior as well as increase in hippocampal volume following either pharmacological or cognitive behavioral therapy in individuals suffering from PTSD (Bremner & Vermetten, 2004; Levy-Gigi, Szabó, Kelemen, & Kéri, 2013).
The Autonomic Nervous System
The autonomic nervous system (ANS) is part of the peripheral nervous system in humans. It is regulated by the hypothalamus and controls our internal organs and glands, including such processes as pulse, blood pressure, breathing, and arousal in response to emotional circumstances. The ANS is generally thought to be outside of voluntary control.
The ANS can be further subdivided into the sympathetic and parasympathetic nervous systems. When activated, the sympathetic nervous system (SNS) controls the endocrine glands to prepare the body for emergency action. SNS activation causes the adrenal glands to produce epinephrine (also known as adrenaline), which results in the “fight-or-flight” response. The fight-or-flight response involves increased blood flow to the muscles, increased heart rate, and other physiological responses that enable the body to move more quickly and feel less pain in situations perceived to be dangerous.
Conversely, the parasympathetic nervous system (PN) functions when the body is relaxed or at rest; it helps the body store energy for future use. Effects of PN activation include increased stomach activity and decreased blood flow to the muscles.
The parasympathetic and sympathetic divisions of the ANS have complementary functions, and they operate in tandem to maintain the body’s equilibrium. Equilibrium of the body, in which biological conditions (such as body temperature) are maintained at optimal levels, is known as homeostasis.
The Reticular Activating System
The reticular activating system (RAS) is a network of neurons that runs through the core of the hindbrain and into the midbrain and forebrain. The RAS is made up of the midbrain reticular formation, the mesencephalic nucleus (mesencephalon), the thalamic intralaminar nucleus (centromedian nucleus), the dorsal hypothalamus, and the tegmentum.
The RAS is involved with arousal and attention, sleep and wakefulness, and the control of reflexes. The RAS is believed to first arouse the cortex and then maintain its wakefulness so that sensory information and emotion can be interpreted more effectively. It helps us fulfill goals by directing our concentration toward them and plays a role in individuals’ responses to situations and events.