{"id":284,"date":"2017-10-23T19:59:39","date_gmt":"2017-10-23T19:59:39","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/sunynutrition\/?post_type=chapter&p=284"},"modified":"2017-11-10T18:38:33","modified_gmt":"2017-11-10T18:38:33","slug":"3-4-small-intestine","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/suny-herkimer-nutritionflex\/chapter\/3-4-small-intestine\/","title":{"raw":"3.4 Small Intestine","rendered":"3.4 Small Intestine"},"content":{"raw":"
\r\n\r\nThe small intestine is the primary site of digestion. It is divided into three sections: the duodenum, jejunum, and ileum (shown below). After leaving the stomach, the first part of the small intestine that chyme will encounter is the duodenum.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"640\"]\"\" Figure 3.41 Three sections of the small intestine1<\/sup>[\/caption]\r\n\r\n<\/div>\r\nThe small intestine consists of many layers, which can be seen in the cross section below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"588\"]\"\" Figure 3.42 Cross section of the small intestine2<\/sup>[\/caption]\r\n\r\n<\/div>\r\nExamining these layers closer, we are going to focus on the epithelium, which comes into contact with the chyme and is responsible for absorption. The lumen is the name of the cavity that is considered \u201coutside the body\u201d that chyme moves through.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"1221\"]\"\" Figure 3.43 Cross section of small intestine with the structures labeled2<\/sup>[\/caption]\r\n\r\n<\/div>\r\nThe organization of the small intestine is in such a way that it contains circular folds and finger-like projections known as villi. The folds and villi are shown in the next few figures.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"839\"]\"\" Figure 3.44 Folds in the small intestine2<\/sup>[\/caption]\r\n\r\n<\/div>\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"328\"]\"\" Figure 3.45 Villi in the small intestine3<\/sup>[\/caption]\r\n\r\n<\/div>\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"1000\"]\"\" Figure 3.46 Villi line the surface of the small intestine2,4<\/sup>[\/caption]\r\n\r\n<\/div>\r\nIf we were to zoom in even closer, we would be able to see that enterocytes (small intestine absorptive cells) line villi as shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"724\"]\"\" Figure 3.47 Enterocytes line villi4<\/sup>[\/caption]\r\n\r\n<\/div>\r\nThe side, or membrane, of the enterocyte that faces the lumen is not smooth either. It is lined with microvilli, and is known as the brush border (aka apical) membrane, as shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"831\"]\"\" Figure 3.48 Enterocyte, or small intestinal absorptive cell is lined with microvilli. This lined surface is referred to as the brush border membrane.[\/caption]\r\n\r\n<\/div>\r\nTogether these features (folds + villi + microvilli) increase the surface area ~600 times versus if it was a smooth tube5<\/sup>. More surface area leads to more contact with the enterocytes and thus, increased absorption.\r\n\r\nGoing even closer, we discover that the surface of the microvilli is covered by the hair-like glycocalyx, which is glycoproteins and carbohydrates as shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"900\"]\"\" Figure 3.49 Glycocalyx lines the microvilli[\/caption]\r\n\r\n<\/div>\r\nNow that you have learned about the anatomy of the small intestine, the following subsections go through the different digestive processes that occur there.\r\n\r\nSubsections:\r\n\r\n3.41 Digestive Hormones, Accessory Organs, & Secretions<\/a>\r\n\r\n3.42 Carbohydrate Digestion in the Small Intestine<\/a>\r\n\r\n3.43 Protein Digestion in the Small Intestine<\/a>\r\n\r\n3.44 Lipid Digestion in the Small Intestine<\/a>\r\n\r\nReferences & Links<\/b>\r\n\r\n1. http:\/\/commons.wikimedia.org\/wiki\/Image:Illu_small_intestine_catal%C3%A0.png\r\n\r\n2. Author unknown, NCI, http:\/\/visualsonline.cancer.gov\/details.cfm?imageid=1781\r\n\r\n3. http:\/\/digestive.niddk.nih.gov\/ddiseases\/pubs\/celiac\/\r\n\r\n4. http:\/\/commons.wikimedia.org\/wiki\/Image:Gray1061.png\r\n\r\n5.\u00a0 Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J. (2009) Wardlaw's perspectives in nutrition. New York, NY: McGraw-Hill.\r\n\r\n<\/div>","rendered":"
\n

The small intestine is the primary site of digestion. It is divided into three sections: the duodenum, jejunum, and ileum (shown below). After leaving the stomach, the first part of the small intestine that chyme will encounter is the duodenum.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.41 Three sections of the small intestine1<\/sup><\/p>\n<\/div>\n<\/div>\n

The small intestine consists of many layers, which can be seen in the cross section below.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.42 Cross section of the small intestine2<\/sup><\/p>\n<\/div>\n<\/div>\n

Examining these layers closer, we are going to focus on the epithelium, which comes into contact with the chyme and is responsible for absorption. The lumen is the name of the cavity that is considered \u201coutside the body\u201d that chyme moves through.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.43 Cross section of small intestine with the structures labeled2<\/sup><\/p>\n<\/div>\n<\/div>\n

The organization of the small intestine is in such a way that it contains circular folds and finger-like projections known as villi. The folds and villi are shown in the next few figures.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.44 Folds in the small intestine2<\/sup><\/p>\n<\/div>\n<\/div>\n

\n
\"\"<\/p>\n

Figure 3.45 Villi in the small intestine3<\/sup><\/p>\n<\/div>\n<\/div>\n

\n
\"\"<\/p>\n

Figure 3.46 Villi line the surface of the small intestine2,4<\/sup><\/p>\n<\/div>\n<\/div>\n

If we were to zoom in even closer, we would be able to see that enterocytes (small intestine absorptive cells) line villi as shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.47 Enterocytes line villi4<\/sup><\/p>\n<\/div>\n<\/div>\n

The side, or membrane, of the enterocyte that faces the lumen is not smooth either. It is lined with microvilli, and is known as the brush border (aka apical) membrane, as shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.48 Enterocyte, or small intestinal absorptive cell is lined with microvilli. This lined surface is referred to as the brush border membrane.<\/p>\n<\/div>\n<\/div>\n

Together these features (folds + villi + microvilli) increase the surface area ~600 times versus if it was a smooth tube5<\/sup>. More surface area leads to more contact with the enterocytes and thus, increased absorption.<\/p>\n

Going even closer, we discover that the surface of the microvilli is covered by the hair-like glycocalyx, which is glycoproteins and carbohydrates as shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 3.49 Glycocalyx lines the microvilli<\/p>\n<\/div>\n<\/div>\n

Now that you have learned about the anatomy of the small intestine, the following subsections go through the different digestive processes that occur there.<\/p>\n

Subsections:<\/p>\n

3.41 Digestive Hormones, Accessory Organs, & Secretions<\/a><\/p>\n

3.42 Carbohydrate Digestion in the Small Intestine<\/a><\/p>\n

3.43 Protein Digestion in the Small Intestine<\/a><\/p>\n

3.44 Lipid Digestion in the Small Intestine<\/a><\/p>\n

References & Links<\/b><\/p>\n

1. http:\/\/commons.wikimedia.org\/wiki\/Image:Illu_small_intestine_catal%C3%A0.png<\/p>\n

2. Author unknown, NCI, http:\/\/visualsonline.cancer.gov\/details.cfm?imageid=1781<\/p>\n

3. http:\/\/digestive.niddk.nih.gov\/ddiseases\/pubs\/celiac\/<\/p>\n

4. http:\/\/commons.wikimedia.org\/wiki\/Image:Gray1061.png<\/p>\n

5.\u00a0 Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J. (2009) Wardlaw’s perspectives in nutrition. New York, NY: McGraw-Hill.<\/p>\n<\/div>\n\n\t\t\t

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Candela Citations<\/h3>\n\t\t\t\t\t
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