{"id":1079,"date":"2017-10-27T16:56:13","date_gmt":"2017-10-27T16:56:13","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/?post_type=chapter&p=1079"},"modified":"2017-11-14T17:59:22","modified_gmt":"2017-11-14T17:59:22","slug":"13-5-magnesium","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/chapter\/13-5-magnesium\/","title":{"raw":"13.5 Magnesium","rendered":"13.5 Magnesium"},"content":{"raw":"
\r\n\r\nMagnesium is an electrolyte, but that is not considered its major function in the body. Green leafy vegetables, beans, nuts, seeds, and whole grains are good sources of magnesium1,2<\/sup>. 40-60% of consumed magnesium is absorbed at normal levels of intake. Magnesium is excreted primarily in urine3<\/sup>.\r\n\r\n55-60% of magnesium in the body is found in bone3<\/sup>. Some (30%) of this bone magnesium is believed to be exchangeable, or can be used to maintain blood concentrations, similar to how calcium in bones can be used to maintain blood concentrations.\r\n\r\nMagnesium helps to stabilize ATP and nucleotides by binding to phosphate groups.\u00a0Magnesium plays a role in over 300 enzymes in the body. Here is a list of some of the physiological processes that magnesium participates in3<\/sup>:\r\n\r\nGlycolysis\r\n\r\nTCA cycle\r\n\r\nFatty acid oxidation (beta-oxidation)\r\n\r\nDNA and RNA transcription\r\n\r\nNucleotide synthesis\r\n\r\nMuscle contraction\r\n\r\nMagnesium deficiency is rare, but can be caused by prolonged diarrhea or vomiting. Symptoms include1<\/sup>:\r\n\r\nIrregular heartbeat\r\n\r\nMuscle spasms\r\n\r\nDisorientation\r\n\r\nSeizures\r\n\r\nNausea\r\n\r\nVomiting\r\n\r\nMagnesium toxicity is also rare but can occur from excessive use of antacids or laxatives. Symptoms include3<\/sup>:\r\n\r\nDiarrhea\r\n\r\nNausea\r\n\r\nFlushing\r\n\r\nDouble vision\r\n\r\nSlurred speech\r\n\r\nWeakness\r\n\r\nParalysis\r\n\r\nMagnesium supplements differ in percent of magnesium in the different forms, as shown below.\r\n
\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"569\"]\"\" Figure 13.51 Percent magnesium in oral supplements[\/caption]\r\n\r\n<\/div>\r\nThe bioavailability of magnesium oxide is significantly lower than magnesium chloride, magnesium lactate, and magnesium aspartate. The latter 3 are equally bioavailable4<\/sup>.\r\n\r\n

References & Links<\/h3>\r\n\r\n1. Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J. (2009) Wardlaw's perspectives in nutrition. New York, NY: McGraw-Hill.\r\n\r\n2. McGuire M, Beerman KA. (2011) Nutritional sciences: From fundamentals to food. Belmont, CA: Wadsworth Cengage Learning.\r\n\r\n3. Gropper SS, Smith JL, Groff JL. (2008) Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Publishing.\r\n\r\n4. http:\/\/www.health-choices-for-life.com\/magnesium_supplements.html\r\n\r\n<\/div>","rendered":"
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Magnesium is an electrolyte, but that is not considered its major function in the body. Green leafy vegetables, beans, nuts, seeds, and whole grains are good sources of magnesium1,2<\/sup>. 40-60% of consumed magnesium is absorbed at normal levels of intake. Magnesium is excreted primarily in urine3<\/sup>.<\/p>\n

55-60% of magnesium in the body is found in bone3<\/sup>. Some (30%) of this bone magnesium is believed to be exchangeable, or can be used to maintain blood concentrations, similar to how calcium in bones can be used to maintain blood concentrations.<\/p>\n

Magnesium helps to stabilize ATP and nucleotides by binding to phosphate groups.\u00a0Magnesium plays a role in over 300 enzymes in the body. Here is a list of some of the physiological processes that magnesium participates in3<\/sup>:<\/p>\n

Glycolysis<\/p>\n

TCA cycle<\/p>\n

Fatty acid oxidation (beta-oxidation)<\/p>\n

DNA and RNA transcription<\/p>\n

Nucleotide synthesis<\/p>\n

Muscle contraction<\/p>\n

Magnesium deficiency is rare, but can be caused by prolonged diarrhea or vomiting. Symptoms include1<\/sup>:<\/p>\n

Irregular heartbeat<\/p>\n

Muscle spasms<\/p>\n

Disorientation<\/p>\n

Seizures<\/p>\n

Nausea<\/p>\n

Vomiting<\/p>\n

Magnesium toxicity is also rare but can occur from excessive use of antacids or laxatives. Symptoms include3<\/sup>:<\/p>\n

Diarrhea<\/p>\n

Nausea<\/p>\n

Flushing<\/p>\n

Double vision<\/p>\n

Slurred speech<\/p>\n

Weakness<\/p>\n

Paralysis<\/p>\n

Magnesium supplements differ in percent of magnesium in the different forms, as shown below.<\/p>\n

\n
\"\"<\/p>\n

Figure 13.51 Percent magnesium in oral supplements<\/p>\n<\/div>\n<\/div>\n

The bioavailability of magnesium oxide is significantly lower than magnesium chloride, magnesium lactate, and magnesium aspartate. The latter 3 are equally bioavailable4<\/sup>.<\/p>\n

References & Links<\/h3>\n

1. Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J. (2009) Wardlaw’s perspectives in nutrition. New York, NY: McGraw-Hill.<\/p>\n

2. McGuire M, Beerman KA. (2011) Nutritional sciences: From fundamentals to food. Belmont, CA: Wadsworth Cengage Learning.<\/p>\n

3. Gropper SS, Smith JL, Groff JL. (2008) Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Publishing.<\/p>\n

4. http:\/\/www.health-choices-for-life.com\/magnesium_supplements.html<\/p>\n<\/div>\n\n\t\t\t

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Candela Citations<\/h3>\n\t\t\t\t\t
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