{"id":377,"date":"2017-10-23T20:19:54","date_gmt":"2017-10-23T20:19:54","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/sunynutrition\/?post_type=chapter&#038;p=377"},"modified":"2017-11-13T19:07:38","modified_gmt":"2017-11-13T19:07:38","slug":"4-6-protein-uptake-absorption-transport-liver-uptake","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/chapter\/4-6-protein-uptake-absorption-transport-liver-uptake\/","title":{"raw":"4.6 Protein Uptake, Absorption, Transport &amp; Liver Uptake","rendered":"4.6 Protein Uptake, Absorption, Transport &amp; Liver Uptake"},"content":{"raw":"<div class=\"__UNKNOWN__\">\r\n\r\nThere are a number of similarities between carbohydrate and protein uptake, absorption, transport, and uptake by the liver. Hopefully after this section you will understand these similarities.\r\n\r\nOver 60% of all amino acids are taken up into the enterocyte as di- and tripeptides through the PepT1 transporter. Individual amino acids are taken up through a variety of amino acid transporters. Once inside the enterocyte, peptidases cleave the peptides to individual amino acids. These cleaved amino acids, along with those that were taken up as individual amino acids, are moved into the capillary by another variety of amino acid transporters (some are the same as on the brush border, some are different).\r\n<div>\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"1135\"]<img src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201915\/100000000000046F000002693CA157FD.png\" alt=\"\" width=\"1135\" height=\"617\" \/> Figure 4.61 Protein uptake and absorption[\/caption]\r\n\r\n<\/div>\r\nThe capillary inside a villus is shown below.\r\n<div>\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"323\"]<img src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201919\/10000201000001430000019BA339853D.png\" alt=\"\" width=\"323\" height=\"411\" \/> Figure 4.62 Anatomy of a villus<sup>1<\/sup>[\/caption]\r\n\r\n<\/div>\r\nLike monosaccharides, amino acids are transported directly to the liver through the portal vein.\r\n<div>\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"826\"]<img src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201921\/100000000000033A000002AD0765EBDD.png\" alt=\"\" width=\"826\" height=\"685\" \/> Figure 4.63 The portal vein transports monosaccharides and amino acids to the liver<sup>2<\/sup>[\/caption]\r\n\r\n<\/div>\r\nAmino acids are taken up into the hepatocyte through a variety of amino acid transporters. The amino acids can then be used to either make proteins or are broken down to produce glucose, as will be described in chapter 6.\r\n<div>\r\n\r\n[caption id=\"\" align=\"aligncenter\" width=\"1118\"]<img src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201923\/100000000000045E0000027C8E8F1B89.png\" alt=\"\" width=\"1118\" height=\"636\" \/> Figure 4.64 Hepatic amino acid uptake[\/caption]\r\n\r\n<\/div>\r\n<h3>References &amp; Links<\/h3>\r\n\r\n1. http:\/\/en.wikipedia.org\/wiki\/File:Intestinal_villus_simplified.svg\r\n\r\n2. https:\/\/commons.wikimedia.org\/wiki\/File:Gray591.png\r\n\r\n<h3>Videos<\/h3>\r\n\r\nAbsorption in the Small Intestine - http:\/\/www.youtube.com\/watch?v=P1sDOJM65Bc\r\n\r\n<\/div>","rendered":"<div class=\"__UNKNOWN__\">\n<p>There are a number of similarities between carbohydrate and protein uptake, absorption, transport, and uptake by the liver. Hopefully after this section you will understand these similarities.<\/p>\n<p>Over 60% of all amino acids are taken up into the enterocyte as di- and tripeptides through the PepT1 transporter. Individual amino acids are taken up through a variety of amino acid transporters. Once inside the enterocyte, peptidases cleave the peptides to individual amino acids. These cleaved amino acids, along with those that were taken up as individual amino acids, are moved into the capillary by another variety of amino acid transporters (some are the same as on the brush border, some are different).<\/p>\n<div>\n<div style=\"width: 1145px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201915\/100000000000046F000002693CA157FD.png\" alt=\"\" width=\"1135\" height=\"617\" \/><\/p>\n<p class=\"wp-caption-text\">Figure 4.61 Protein uptake and absorption<\/p>\n<\/div>\n<\/div>\n<p>The capillary inside a villus is shown below.<\/p>\n<div>\n<div style=\"width: 333px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201919\/10000201000001430000019BA339853D.png\" alt=\"\" width=\"323\" height=\"411\" \/><\/p>\n<p class=\"wp-caption-text\">Figure 4.62 Anatomy of a villus<sup>1<\/sup><\/p>\n<\/div>\n<\/div>\n<p>Like monosaccharides, amino acids are transported directly to the liver through the portal vein.<\/p>\n<div>\n<div style=\"width: 836px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201921\/100000000000033A000002AD0765EBDD.png\" alt=\"\" width=\"826\" height=\"685\" \/><\/p>\n<p class=\"wp-caption-text\">Figure 4.63 The portal vein transports monosaccharides and amino acids to the liver<sup>2<\/sup><\/p>\n<\/div>\n<\/div>\n<p>Amino acids are taken up into the hepatocyte through a variety of amino acid transporters. The amino acids can then be used to either make proteins or are broken down to produce glucose, as will be described in chapter 6.<\/p>\n<div>\n<div style=\"width: 1128px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/2569\/2017\/10\/23201923\/100000000000045E0000027C8E8F1B89.png\" alt=\"\" width=\"1118\" height=\"636\" \/><\/p>\n<p class=\"wp-caption-text\">Figure 4.64 Hepatic amino acid uptake<\/p>\n<\/div>\n<\/div>\n<h3>References &amp; Links<\/h3>\n<p>1. http:\/\/en.wikipedia.org\/wiki\/File:Intestinal_villus_simplified.svg<\/p>\n<p>2. https:\/\/commons.wikimedia.org\/wiki\/File:Gray591.png<\/p>\n<h3>Videos<\/h3>\n<p>Absorption in the Small Intestine &#8211; http:\/\/www.youtube.com\/watch?v=P1sDOJM65Bc<\/p>\n<\/div>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-377\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Kansas State University Human Nutrition Flexbook. <strong>Authored by<\/strong>: Brian Lindshield. <strong>Provided by<\/strong>: Kansas State University. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"http:\/\/goo.gl\/vOAnR\">http:\/\/goo.gl\/vOAnR<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section>","protected":false},"author":311,"menu_order":12,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Kansas State University Human Nutrition Flexbook\",\"author\":\"Brian Lindshield\",\"organization\":\"Kansas State University\",\"url\":\"goo.gl\/vOAnR\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"}]","CANDELA_OUTCOMES_GUID":"","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-377","chapter","type-chapter","status-publish","hentry"],"part":339,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapters\/377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/wp\/v2\/users\/311"}],"version-history":[{"count":5,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapters\/377\/revisions"}],"predecessor-version":[{"id":1707,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapters\/377\/revisions\/1707"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/parts\/339"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapters\/377\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/wp\/v2\/media?parent=377"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/pressbooks\/v2\/chapter-type?post=377"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/wp\/v2\/contributor?post=377"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/suny-nutrition\/wp-json\/wp\/v2\/license?post=377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}