{"id":312,"date":"2016-10-10T20:07:00","date_gmt":"2016-10-10T20:07:00","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/math4libarts\/?post_type=chapter&#038;p=312"},"modified":"2019-05-30T16:58:21","modified_gmt":"2019-05-30T16:58:21","slug":"experiments","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/chapter\/experiments\/","title":{"raw":"Experiments","rendered":"Experiments"},"content":{"raw":"<div class=\"textbox learning-objectives\">\r\n<h3>Learning Outcomes<\/h3>\r\n<ul>\r\n \t<li>Identify\u00a0methods for obtaining a random sample of the intended population of a study<\/li>\r\n \t<li>Identify ineffective ways of obtaining a random sample from a population<\/li>\r\n \t<li>Identify types of sample bias<\/li>\r\n \t<li>Identify the differences between observational study and an experiment<\/li>\r\n \t<li>Identify the treatment in an experiment<\/li>\r\n \t<li>Determine whether an experiment may have been influenced by confounding<\/li>\r\n<\/ul>\r\n<\/div>\r\n<h2>Observing vs. Acting<\/h2>\r\nSo far, we have primarily discussed <strong>observational studies<\/strong> \u2013 studies in which conclusions would be drawn from observations of a sample or the population. In some cases these observations might be unsolicited, such as studying the percentage of cars that turn right at a red light even when there is a \u201cno turn on red\u201d sign. In other cases the observations are solicited, like in a survey or a poll.\r\n\r\nIn contrast, it is common to use <strong>experiments<\/strong> when exploring how subjects react to an outside influence. In an experiment, some kind of <strong>treatment<\/strong> is applied to the subjects and the results are measured and recorded.\r\n\r\n<a href=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/1141\/2016\/12\/30181148\/lab-217041_640.jpg\"><img class=\"aligncenter size-full wp-image-1033\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/1141\/2016\/12\/30181148\/lab-217041_640.jpg\" alt=\"Collection of clear glass scientific measuring equipment, with clear liquid in them\" width=\"640\" height=\"423\" \/><\/a>\r\n<div>\r\n<div class=\"textbox\">\r\n<div>\r\n<h3>Observational studies and experiments<\/h3>\r\n<\/div>\r\n<div>\r\n<ul>\r\n \t<li>An <strong>observational study<\/strong> is a study based on observations or measurements<\/li>\r\n \t<li>An <strong>experiment<\/strong> is a study in which the effects of a <strong>treatment<\/strong> are measured<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>Examples<\/h3>\r\nHere are some examples of experiments:\r\n\r\nA pharmaceutical company tests a new medicine for treating Alzheimer\u2019s disease by administering the drug to 50 elderly patients with recent diagnoses. The treatment here is the new drug.\r\n\r\n<hr \/>\r\n\r\nA gym tests out a new weight loss program by enlisting 30 volunteers to try out the program. The treatment here is the new program.\r\n\r\n<hr \/>\r\n\r\nYou test a new kitchen cleaner by buying a bottle and cleaning your kitchen. The new cleaner is the treatment.\r\n\r\n<hr \/>\r\n\r\nA psychology researcher explores the effect of music on temperament by measuring people\u2019s temperament while listening to different types of music. The music is the treatment.\r\n\r\n<\/div>\r\n&nbsp;\r\n\r\nThese examples are discussed further in the following video.\r\n\r\nhttps:\/\/youtu.be\/HSTTKzsdHEw\r\n<div class=\"textbox key-takeaways\">\r\n<h3>Try It<\/h3>\r\nIs each scenario describing an observational study or an experiment?\r\n\r\na. The weights of 30 randomly selected people are measured\r\n\r\nb. Subjects are asked to do 20 jumping jacks, and then their heart rates are measured\r\n\r\nc. Twenty coffee drinkers and twenty tea drinkers are given a concentration test\r\n[reveal-answer q=\"713031\"]Show Solution[\/reveal-answer]\r\n[hidden-answer a=\"713031\"]\r\n\r\na. Observational study\r\n<div>\r\n\r\nb. Experiment; the treatment is the jumping jacks\r\n\r\nc. Experiment; the treatments are coffee and tea\r\n\r\n<\/div>\r\n[\/hidden-answer]\r\n\r\n<iframe id=\"mom1\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6914&amp;theme=oea&amp;iframe_resize_id=mom1\" width=\"100%\" height=\"250\"><\/iframe>\r\n\r\n<\/div>\r\nWhen conducting experiments, it is essential to isolate the treatment being tested.\r\n<div class=\"textbox exercises\">\r\n<h3>example<\/h3>\r\nSuppose a middle school (junior high) finds that their students are not scoring well on the state\u2019s standardized math test. They decide to run an experiment to see if an alternate curriculum would improve scores. To run the test, they hire a math specialist to come in and teach a class using the new curriculum. To their delight, they see an improvement in test scores.\r\n\r\n<\/div>\r\nThe difficulty with this scenario is that it is not clear whether the curriculum is responsible for the improvement, or whether the improvement is due to a math specialist teaching the class. This is called <strong>confounding<\/strong> \u2013 when it is not clear which factor or factors caused the observed effect. Confounding is the downfall of many experiments, though sometimes it is hidden.\r\n<div class=\"textbox\">\r\n<h3>Confounding<\/h3>\r\n<strong>Confounding<\/strong> occurs when there are two potential variables that could have caused the outcome and it is not possible to determine which actually caused the result.\r\n\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>examples<\/h3>\r\nA drug company study about a weight loss pill might report that people lost an average of 8 pounds while using their new drug. However, in the fine print you find a statement saying that participants were encouraged to also diet and exercise. It is not clear in this case whether the weight loss is due to the pill, to diet and exercise, or a combination of both. In this case confounding has occurred.\r\n\r\n&nbsp;\r\n\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>Example<\/h3>\r\nResearchers conduct an experiment to determine whether students will perform better on an arithmetic test if they listen to music during the test. They first give the student a test without music, then give a similar test while the student listens to music. In this case, the student might perform better on the second test, regardless of the music, simply because it was the second test and they were warmed up.\r\n\r\n<\/div>\r\nView the following for additional discussion of these examples.\r\n\r\nhttps:\/\/youtu.be\/SrCm12HZay0\r\n<div class=\"textbox key-takeaways\">\r\n<h3>Try It<\/h3>\r\n<iframe id=\"mom10\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6736&amp;theme=oea&amp;iframe_resize_id=mom10\" width=\"100%\" height=\"250\"><\/iframe>\r\n\r\n<\/div>\r\n<div>There are a number of measures that can be introduced to help reduce the likelihood of confounding. The primary measure is to use a <strong>control group<\/strong>.<\/div>\r\n<div class=\"textbox\">\r\n<h3>Control group<\/h3>\r\nWhen using a control group, the participants are divided into two or more groups, typically a <strong>control group<\/strong> and a treatment group. The treatment group receives the treatment being tested; the control group does not receive the treatment.\r\n\r\n<\/div>\r\nIdeally, the groups are otherwise as similar as possible, isolating the treatment as the only potential source of difference between the groups. For this reason, the method of dividing groups is important. Some researchers attempt to ensure that the groups have similar characteristics (same number of females, same number of people over 50, etc.), but it is nearly impossible to control for every characteristic. Because of this, random assignment is very commonly used.\r\n<div class=\"textbox exercises\">\r\n<h3>examples<\/h3>\r\nTo determine if a two day prep course would help high school students improve their scores on the SAT test, a group of students was randomly divided into two subgroups. The first group, the treatment group, was given a two day prep course. The second group, the control group, was not given the prep course. Afterwards, both groups were given the SAT.\r\n\r\n<hr \/>\r\n\r\nA company testing a new plant food grows two crops of plants in adjacent fields, the treatment group receiving the new plant food and the control group not. The crop yield would then be compared. By growing them at the same time in adjacent fields, they are controlling for weather and other confounding factors.\r\n\r\n<\/div>\r\nSometimes not giving the control group anything does not completely control for confounding variables. For example, suppose a medicine study is testing a new headache pill by giving the treatment group the pill and the control group nothing. If the treatment group showed improvement, we would not know whether it was due to the medicine in the pill, or a response to have taken any pill. This is called a <strong>placebo effect<\/strong>.\r\n<div>\r\n<div class=\"textbox\">\r\n<div>\r\n<h3>Placebo effect<\/h3>\r\n<\/div>\r\n<div>\r\n\r\nThe <strong>placebo effect<\/strong> is when the effectiveness of a treatment is influenced by the patient\u2019s perception of how effective they think the treatment will be, so a result might be seen even if the treatment is ineffectual.\r\n\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>example<\/h3>\r\nA study found that when doing painful dental tooth extractions, patients told they were receiving a strong painkiller while actually receiving a saltwater injection found as much pain relief as patients receiving a dose of morphine.[footnote]Levine JD, Gordon NC, Smith R, Fields HL. (1981) Analgesic responses to morphine and placebo in individuals with postoperative pain. Pain. 10:379-89.[\/footnote]\r\n\r\n<\/div>\r\n<\/div>\r\nTo control for the placebo effect, a <strong>placebo<\/strong>, or dummy treatment, is often given to the control group. This way, both groups are truly identical except for the specific treatment given.\r\n<div>\r\n<div class=\"textbox\">\r\n<div>\r\n<h3>Placebo and Placebo controlled experiments<\/h3>\r\n<\/div>\r\n<div>\r\n<ul>\r\n \t<li>A <strong>placebo<\/strong> is a dummy treatment given to control for the placebo effect.<\/li>\r\n \t<li>An experiment that gives the control group a placebo is called a <strong>placebo controlled experiment<\/strong>.<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>examples<\/h3>\r\nIn a study for a new medicine that is dispensed in a pill form, a sugar pill could be used as a placebo.\r\n\r\n<hr \/>\r\n\r\nIn a study on the effect of alcohol on memory, a non-alcoholic beer might be given to the control group as a placebo.\r\n\r\n<hr \/>\r\n\r\nIn a study of a frozen meal diet plan, the treatment group would receive the diet food, and the control could be given standard frozen meals stripped of their original packaging.\r\n\r\nThe following video walks through the controlled experiment scenarios, including the ones using placebos.\r\n\r\nhttps:\/\/youtu.be\/UkCHUeqMb5Y\r\n\r\n<\/div>\r\nIn some cases, it is more appropriate to compare to a conventional treatment than a placebo. For example, in a cancer research study, it would not be ethical to deny any treatment to the control group or to give a placebo treatment. In this case, the currently acceptable medicine would be given to the second group, called a <strong>comparison group<\/strong> in this case. In our SAT test example, the non-treatment group would most likely be encouraged to study on their own, rather than be asked to not study at all, to provide a meaningful comparison.\r\n\r\n<\/div>\r\nWhen using a placebo, it would defeat the purpose if the participant knew they were receiving the placebo.\r\n<div>\r\n<div class=\"textbox\">\r\n<div>\r\n<h3>Blind studies<\/h3>\r\n<\/div>\r\n<div>\r\n<ul>\r\n \t<li>A <strong>blind study<\/strong> is one in which the participant does not know whether or not they are receiving the treatment or a placebo.<\/li>\r\n \t<li>A <strong>double-blind study<\/strong> is one in which those interacting with the participants don\u2019t know who is in the treatment group and who is in the control group.<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox exercises\">\r\n<h3>examples<\/h3>\r\n<div>\r\n\r\nIn a study about anti-depression medicine, you would not want the psychological evaluator to know whether the patient is in the treatment or control group either, as it might influence their evaluation, so the experiment should be conducted as a double-blind study.\r\n\r\n<\/div>\r\n\r\n<hr \/>\r\n\r\nIt should be noted that not every experiment needs a control group.\r\n\r\nIf a researcher is testing whether a new fabric can withstand fire, she simply needs to torch multiple samples of the fabric \u2013 there is no need for a control group.\r\n\r\nThese examples are demonstrated in the following video.\r\n\r\nhttps:\/\/youtu.be\/7BFZVGCxeYc\r\n\r\n<\/div>\r\n<div class=\"textbox key-takeaways\">\r\n<h3>Try It now<\/h3>\r\nTo test a new lie detector, two groups of subjects are given the new test. One group is asked to answer all the questions truthfully, and the second group is asked to lie on one set of questions. The person administering the lie detector test does not know what group each subject is in.\r\n\r\nDoes this experiment have a control group? Is it blind, double-blind, or neither?\r\n[reveal-answer q=\"514145\"]Show Solution[\/reveal-answer]\r\n[hidden-answer a=\"514145\"]\r\n&lt;div&gt;\r\n\r\nThe truth-telling group could be considered the control group, but really both groups are treatment groups here, since it is important for the lie detector to be able to correctly identify lies, and also not identify truth telling as lying. This study is blind, since the person running the test does not know what group each subject is in.\r\n[\/hidden-answer]\r\n\r\n<iframe id=\"mom50\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6728&amp;theme=oea&amp;iframe_resize_id=mom50\" width=\"100%\" height=\"250\"><\/iframe>\r\n\r\n<\/div>\r\n<\/div>","rendered":"<div class=\"textbox learning-objectives\">\n<h3>Learning Outcomes<\/h3>\n<ul>\n<li>Identify\u00a0methods for obtaining a random sample of the intended population of a study<\/li>\n<li>Identify ineffective ways of obtaining a random sample from a population<\/li>\n<li>Identify types of sample bias<\/li>\n<li>Identify the differences between observational study and an experiment<\/li>\n<li>Identify the treatment in an experiment<\/li>\n<li>Determine whether an experiment may have been influenced by confounding<\/li>\n<\/ul>\n<\/div>\n<h2>Observing vs. Acting<\/h2>\n<p>So far, we have primarily discussed <strong>observational studies<\/strong> \u2013 studies in which conclusions would be drawn from observations of a sample or the population. In some cases these observations might be unsolicited, such as studying the percentage of cars that turn right at a red light even when there is a \u201cno turn on red\u201d sign. In other cases the observations are solicited, like in a survey or a poll.<\/p>\n<p>In contrast, it is common to use <strong>experiments<\/strong> when exploring how subjects react to an outside influence. In an experiment, some kind of <strong>treatment<\/strong> is applied to the subjects and the results are measured and recorded.<\/p>\n<p><a href=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/1141\/2016\/12\/30181148\/lab-217041_640.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1033\" src=\"https:\/\/s3-us-west-2.amazonaws.com\/courses-images\/wp-content\/uploads\/sites\/1141\/2016\/12\/30181148\/lab-217041_640.jpg\" alt=\"Collection of clear glass scientific measuring equipment, with clear liquid in them\" width=\"640\" height=\"423\" \/><\/a><\/p>\n<div>\n<div class=\"textbox\">\n<div>\n<h3>Observational studies and experiments<\/h3>\n<\/div>\n<div>\n<ul>\n<li>An <strong>observational study<\/strong> is a study based on observations or measurements<\/li>\n<li>An <strong>experiment<\/strong> is a study in which the effects of a <strong>treatment<\/strong> are measured<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>Examples<\/h3>\n<p>Here are some examples of experiments:<\/p>\n<p>A pharmaceutical company tests a new medicine for treating Alzheimer\u2019s disease by administering the drug to 50 elderly patients with recent diagnoses. The treatment here is the new drug.<\/p>\n<hr \/>\n<p>A gym tests out a new weight loss program by enlisting 30 volunteers to try out the program. The treatment here is the new program.<\/p>\n<hr \/>\n<p>You test a new kitchen cleaner by buying a bottle and cleaning your kitchen. The new cleaner is the treatment.<\/p>\n<hr \/>\n<p>A psychology researcher explores the effect of music on temperament by measuring people\u2019s temperament while listening to different types of music. The music is the treatment.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p>These examples are discussed further in the following video.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-1\" title=\"Experiments\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/HSTTKzsdHEw?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<div class=\"textbox key-takeaways\">\n<h3>Try It<\/h3>\n<p>Is each scenario describing an observational study or an experiment?<\/p>\n<p>a. The weights of 30 randomly selected people are measured<\/p>\n<p>b. Subjects are asked to do 20 jumping jacks, and then their heart rates are measured<\/p>\n<p>c. Twenty coffee drinkers and twenty tea drinkers are given a concentration test<\/p>\n<div class=\"qa-wrapper\" style=\"display: block\"><span class=\"show-answer collapsed\" style=\"cursor: pointer\" data-target=\"q713031\">Show Solution<\/span><\/p>\n<div id=\"q713031\" class=\"hidden-answer\" style=\"display: none\">\n<p>a. Observational study<\/p>\n<div>\n<p>b. Experiment; the treatment is the jumping jacks<\/p>\n<p>c. Experiment; the treatments are coffee and tea<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p><iframe loading=\"lazy\" id=\"mom1\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6914&amp;theme=oea&amp;iframe_resize_id=mom1\" width=\"100%\" height=\"250\"><\/iframe><\/p>\n<\/div>\n<p>When conducting experiments, it is essential to isolate the treatment being tested.<\/p>\n<div class=\"textbox exercises\">\n<h3>example<\/h3>\n<p>Suppose a middle school (junior high) finds that their students are not scoring well on the state\u2019s standardized math test. They decide to run an experiment to see if an alternate curriculum would improve scores. To run the test, they hire a math specialist to come in and teach a class using the new curriculum. To their delight, they see an improvement in test scores.<\/p>\n<\/div>\n<p>The difficulty with this scenario is that it is not clear whether the curriculum is responsible for the improvement, or whether the improvement is due to a math specialist teaching the class. This is called <strong>confounding<\/strong> \u2013 when it is not clear which factor or factors caused the observed effect. Confounding is the downfall of many experiments, though sometimes it is hidden.<\/p>\n<div class=\"textbox\">\n<h3>Confounding<\/h3>\n<p><strong>Confounding<\/strong> occurs when there are two potential variables that could have caused the outcome and it is not possible to determine which actually caused the result.<\/p>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>examples<\/h3>\n<p>A drug company study about a weight loss pill might report that people lost an average of 8 pounds while using their new drug. However, in the fine print you find a statement saying that participants were encouraged to also diet and exercise. It is not clear in this case whether the weight loss is due to the pill, to diet and exercise, or a combination of both. In this case confounding has occurred.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>Example<\/h3>\n<p>Researchers conduct an experiment to determine whether students will perform better on an arithmetic test if they listen to music during the test. They first give the student a test without music, then give a similar test while the student listens to music. In this case, the student might perform better on the second test, regardless of the music, simply because it was the second test and they were warmed up.<\/p>\n<\/div>\n<p>View the following for additional discussion of these examples.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-2\" title=\"Confounding\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/SrCm12HZay0?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<div class=\"textbox key-takeaways\">\n<h3>Try It<\/h3>\n<p><iframe loading=\"lazy\" id=\"mom10\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6736&amp;theme=oea&amp;iframe_resize_id=mom10\" width=\"100%\" height=\"250\"><\/iframe><\/p>\n<\/div>\n<div>There are a number of measures that can be introduced to help reduce the likelihood of confounding. The primary measure is to use a <strong>control group<\/strong>.<\/div>\n<div class=\"textbox\">\n<h3>Control group<\/h3>\n<p>When using a control group, the participants are divided into two or more groups, typically a <strong>control group<\/strong> and a treatment group. The treatment group receives the treatment being tested; the control group does not receive the treatment.<\/p>\n<\/div>\n<p>Ideally, the groups are otherwise as similar as possible, isolating the treatment as the only potential source of difference between the groups. For this reason, the method of dividing groups is important. Some researchers attempt to ensure that the groups have similar characteristics (same number of females, same number of people over 50, etc.), but it is nearly impossible to control for every characteristic. Because of this, random assignment is very commonly used.<\/p>\n<div class=\"textbox exercises\">\n<h3>examples<\/h3>\n<p>To determine if a two day prep course would help high school students improve their scores on the SAT test, a group of students was randomly divided into two subgroups. The first group, the treatment group, was given a two day prep course. The second group, the control group, was not given the prep course. Afterwards, both groups were given the SAT.<\/p>\n<hr \/>\n<p>A company testing a new plant food grows two crops of plants in adjacent fields, the treatment group receiving the new plant food and the control group not. The crop yield would then be compared. By growing them at the same time in adjacent fields, they are controlling for weather and other confounding factors.<\/p>\n<\/div>\n<p>Sometimes not giving the control group anything does not completely control for confounding variables. For example, suppose a medicine study is testing a new headache pill by giving the treatment group the pill and the control group nothing. If the treatment group showed improvement, we would not know whether it was due to the medicine in the pill, or a response to have taken any pill. This is called a <strong>placebo effect<\/strong>.<\/p>\n<div>\n<div class=\"textbox\">\n<div>\n<h3>Placebo effect<\/h3>\n<\/div>\n<div>\n<p>The <strong>placebo effect<\/strong> is when the effectiveness of a treatment is influenced by the patient\u2019s perception of how effective they think the treatment will be, so a result might be seen even if the treatment is ineffectual.<\/p>\n<\/div>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>example<\/h3>\n<p>A study found that when doing painful dental tooth extractions, patients told they were receiving a strong painkiller while actually receiving a saltwater injection found as much pain relief as patients receiving a dose of morphine.<a class=\"footnote\" title=\"Levine JD, Gordon NC, Smith R, Fields HL. (1981) Analgesic responses to morphine and placebo in individuals with postoperative pain. Pain. 10:379-89.\" id=\"return-footnote-312-1\" href=\"#footnote-312-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/p>\n<\/div>\n<\/div>\n<p>To control for the placebo effect, a <strong>placebo<\/strong>, or dummy treatment, is often given to the control group. This way, both groups are truly identical except for the specific treatment given.<\/p>\n<div>\n<div class=\"textbox\">\n<div>\n<h3>Placebo and Placebo controlled experiments<\/h3>\n<\/div>\n<div>\n<ul>\n<li>A <strong>placebo<\/strong> is a dummy treatment given to control for the placebo effect.<\/li>\n<li>An experiment that gives the control group a placebo is called a <strong>placebo controlled experiment<\/strong>.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>examples<\/h3>\n<p>In a study for a new medicine that is dispensed in a pill form, a sugar pill could be used as a placebo.<\/p>\n<hr \/>\n<p>In a study on the effect of alcohol on memory, a non-alcoholic beer might be given to the control group as a placebo.<\/p>\n<hr \/>\n<p>In a study of a frozen meal diet plan, the treatment group would receive the diet food, and the control could be given standard frozen meals stripped of their original packaging.<\/p>\n<p>The following video walks through the controlled experiment scenarios, including the ones using placebos.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-3\" title=\"Controlled Experiments\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/UkCHUeqMb5Y?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<\/div>\n<p>In some cases, it is more appropriate to compare to a conventional treatment than a placebo. For example, in a cancer research study, it would not be ethical to deny any treatment to the control group or to give a placebo treatment. In this case, the currently acceptable medicine would be given to the second group, called a <strong>comparison group<\/strong> in this case. In our SAT test example, the non-treatment group would most likely be encouraged to study on their own, rather than be asked to not study at all, to provide a meaningful comparison.<\/p>\n<\/div>\n<p>When using a placebo, it would defeat the purpose if the participant knew they were receiving the placebo.<\/p>\n<div>\n<div class=\"textbox\">\n<div>\n<h3>Blind studies<\/h3>\n<\/div>\n<div>\n<ul>\n<li>A <strong>blind study<\/strong> is one in which the participant does not know whether or not they are receiving the treatment or a placebo.<\/li>\n<li>A <strong>double-blind study<\/strong> is one in which those interacting with the participants don\u2019t know who is in the treatment group and who is in the control group.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"textbox exercises\">\n<h3>examples<\/h3>\n<div>\n<p>In a study about anti-depression medicine, you would not want the psychological evaluator to know whether the patient is in the treatment or control group either, as it might influence their evaluation, so the experiment should be conducted as a double-blind study.<\/p>\n<\/div>\n<hr \/>\n<p>It should be noted that not every experiment needs a control group.<\/p>\n<p>If a researcher is testing whether a new fabric can withstand fire, she simply needs to torch multiple samples of the fabric \u2013 there is no need for a control group.<\/p>\n<p>These examples are demonstrated in the following video.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-4\" title=\"Blind Experiments\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/7BFZVGCxeYc?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<\/div>\n<div class=\"textbox key-takeaways\">\n<h3>Try It now<\/h3>\n<p>To test a new lie detector, two groups of subjects are given the new test. One group is asked to answer all the questions truthfully, and the second group is asked to lie on one set of questions. The person administering the lie detector test does not know what group each subject is in.<\/p>\n<p>Does this experiment have a control group? Is it blind, double-blind, or neither?<\/p>\n<div class=\"qa-wrapper\" style=\"display: block\"><span class=\"show-answer collapsed\" style=\"cursor: pointer\" data-target=\"q514145\">Show Solution<\/span><\/p>\n<div id=\"q514145\" class=\"hidden-answer\" style=\"display: none\">\n&lt;div&gt;<\/p>\n<p>The truth-telling group could be considered the control group, but really both groups are treatment groups here, since it is important for the lie detector to be able to correctly identify lies, and also not identify truth telling as lying. This study is blind, since the person running the test does not know what group each subject is in.\n<\/p><\/div>\n<\/div>\n<p><iframe loading=\"lazy\" id=\"mom50\" class=\"resizable\" src=\"https:\/\/www.myopenmath.com\/multiembedq.php?id=6728&amp;theme=oea&amp;iframe_resize_id=mom50\" width=\"100%\" height=\"250\"><\/iframe><\/p>\n<\/div>\n<\/div>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-312\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Original<\/div><ul class=\"citation-list\"><li>Revision and Adaptation. <strong>Provided by<\/strong>: Lumen Learning. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><\/ul><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Experiments. <strong>Authored by<\/strong>: David Lippman. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"http:\/\/www.opentextbookstore.com\/mathinsociety\/\">http:\/\/www.opentextbookstore.com\/mathinsociety\/<\/a>. <strong>Project<\/strong>: Math in Society. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/\">CC BY-SA: Attribution-ShareAlike<\/a><\/em><\/li><li>lab-research-chemistry-test. <strong>Authored by<\/strong>: PublicDomainPictures. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/pixabay.com\/en\/lab-research-chemistry-test-217041\/\">https:\/\/pixabay.com\/en\/lab-research-chemistry-test-217041\/<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/about\/cc0\">CC0: No Rights Reserved<\/a><\/em><\/li><li>Experiments. <strong>Authored by<\/strong>: OCLPhase2&#039;s channel. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/youtu.be\/HSTTKzsdHEw\">https:\/\/youtu.be\/HSTTKzsdHEw<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><li>Confounding. <strong>Authored by<\/strong>: OCLPhase2&#039;s channel. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/youtu.be\/SrCm12HZay0\">https:\/\/youtu.be\/SrCm12HZay0<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><li>Controlled Experiments. <strong>Authored by<\/strong>: OCLPhase2&#039;s channel. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/youtu.be\/UkCHUeqMb5Y\">https:\/\/youtu.be\/UkCHUeqMb5Y<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><li>Blind Experiments. <strong>Authored by<\/strong>: OCLPhase2&#039;s channel. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/youtu.be\/7BFZVGCxeYc\">https:\/\/youtu.be\/7BFZVGCxeYc<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><li>Question ID 6736, 6728, 6914. <strong>Authored by<\/strong>: Lippman, David. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em>. <strong>License Terms<\/strong>: IMathAS Community License CC-BY + GPL<\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section><hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-312-1\">Levine JD, Gordon NC, Smith R, Fields HL. (1981) Analgesic responses to morphine and placebo in individuals with postoperative pain. Pain. 10:379-89. <a href=\"#return-footnote-312-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":20,"menu_order":7,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Experiments\",\"author\":\"David Lippman\",\"organization\":\"\",\"url\":\"http:\/\/www.opentextbookstore.com\/mathinsociety\/\",\"project\":\"Math in Society\",\"license\":\"cc-by-sa\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"lab-research-chemistry-test\",\"author\":\"PublicDomainPictures\",\"organization\":\"\",\"url\":\"https:\/\/pixabay.com\/en\/lab-research-chemistry-test-217041\/\",\"project\":\"\",\"license\":\"cc0\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Experiments\",\"author\":\"OCLPhase2\\'s channel\",\"organization\":\"\",\"url\":\"https:\/\/youtu.be\/HSTTKzsdHEw\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Confounding\",\"author\":\"OCLPhase2\\'s channel\",\"organization\":\"\",\"url\":\"https:\/\/youtu.be\/SrCm12HZay0\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Controlled Experiments\",\"author\":\"OCLPhase2\\'s channel\",\"organization\":\"\",\"url\":\"https:\/\/youtu.be\/UkCHUeqMb5Y\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Blind Experiments\",\"author\":\"OCLPhase2\\'s channel\",\"organization\":\"\",\"url\":\"https:\/\/youtu.be\/7BFZVGCxeYc\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Question ID 6736, 6728, 6914\",\"author\":\"Lippman, David\",\"organization\":\"\",\"url\":\"\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"IMathAS Community License CC-BY + GPL\"},{\"type\":\"original\",\"description\":\"Revision and Adaptation\",\"author\":\"\",\"organization\":\"Lumen Learning\",\"url\":\"\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"}]","CANDELA_OUTCOMES_GUID":"81b9ffbd-0bca-4913-af9b-6272f00fdb29","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-312","chapter","type-chapter","status-publish","hentry"],"part":299,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapters\/312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/wp\/v2\/users\/20"}],"version-history":[{"count":10,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapters\/312\/revisions"}],"predecessor-version":[{"id":3027,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapters\/312\/revisions\/3027"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/parts\/299"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapters\/312\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/wp\/v2\/media?parent=312"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/pressbooks\/v2\/chapter-type?post=312"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/wp\/v2\/contributor?post=312"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/waymakermath4libarts\/wp-json\/wp\/v2\/license?post=312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}