{"id":2387,"date":"2016-05-24T20:31:48","date_gmt":"2016-05-24T20:31:48","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/biologyxwaymakerxmaster\/?post_type=chapter&#038;p=2387"},"modified":"2024-04-26T22:29:08","modified_gmt":"2024-04-26T22:29:08","slug":"reading-interphase","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/wm-biology1\/chapter\/reading-interphase\/","title":{"raw":"Interphase","rendered":"Interphase"},"content":{"raw":"<div class=\"textbox learning-objectives\">\r\n<h3>Learning Outcomes<\/h3>\r\n<ul>\r\n \t<li>Identify the characteristics and sub-phases of interphase<\/li>\r\n<\/ul>\r\n<\/div>\r\nDuring interphase, the cell undergoes normal growth processes while also preparing for cell division. In order for a cell to move from interphase into the mitotic phase, many internal and external conditions must be met. The three stages of interphase are called G<sub>1<\/sub>, S, and G<sub>2<\/sub>.\r\n<h2>G<sub>1<\/sub> Phase (First Gap)<\/h2>\r\nThe first stage of interphase is called the\u00a0<strong>G<sub>1<\/sub> phase<\/strong> (first gap) because, from a microscopic aspect, little change is visible. However, during the G<sub>1<\/sub> stage, the cell is quite active at the biochemical level. The cell is accumulating the building blocks of chromosomal DNA and the associated proteins as well as accumulating sufficient energy reserves to complete the task of replicating each chromosome in the nucleus.\r\n<h2>S Phase (Synthesis of DNA)<\/h2>\r\nThroughout interphase, nuclear DNA remains in a semi-condensed chromatin configuration. In the\u00a0<strong>S phase<\/strong>, DNA replication can proceed through the mechanisms that result in the formation of identical pairs of DNA molecules\u2014sister chromatids\u2014that are firmly attached to the centromeric region. The centrosome is duplicated during the S phase. The two centrosomes will give rise to the <strong>mitotic spindle<\/strong>, the apparatus that orchestrates the movement of chromosomes during mitosis. At the center of each animal cell, the centrosomes of animal cells are associated with a pair of rod-like objects, the <strong>centrioles<\/strong>, which are at right angles to each other. Centrioles help organize cell division. Centrioles are not present in the centrosomes of other eukaryotic species, such as plants and most fungi.\r\n<h2>G<sub>2<\/sub> Phase (Second Gap)<\/h2>\r\nIn the\u00a0<strong>G<sub>2<\/sub> phase<\/strong>, the cell replenishes its energy stores and synthesizes proteins necessary for chromosome manipulation. Some cell organelles are duplicated, and the cytoskeleton is dismantled to provide resources for the mitotic phase. There may be additional cell growth during G<sub>2<\/sub>. The final preparations for the mitotic phase must be completed before the cell is able to enter the first stage of mitosis.\r\n<div class=\"textbox tryit\">\r\n<h3>Try It<\/h3>\r\nhttps:\/\/assess.lumenlearning.com\/practice\/7ea20303-9e11-4ca3-b0f5-4a895cda6cbb\r\n<\/div>","rendered":"<div class=\"textbox learning-objectives\">\n<h3>Learning Outcomes<\/h3>\n<ul>\n<li>Identify the characteristics and sub-phases of interphase<\/li>\n<\/ul>\n<\/div>\n<p>During interphase, the cell undergoes normal growth processes while also preparing for cell division. In order for a cell to move from interphase into the mitotic phase, many internal and external conditions must be met. The three stages of interphase are called G<sub>1<\/sub>, S, and G<sub>2<\/sub>.<\/p>\n<h2>G<sub>1<\/sub> Phase (First Gap)<\/h2>\n<p>The first stage of interphase is called the\u00a0<strong>G<sub>1<\/sub> phase<\/strong> (first gap) because, from a microscopic aspect, little change is visible. However, during the G<sub>1<\/sub> stage, the cell is quite active at the biochemical level. The cell is accumulating the building blocks of chromosomal DNA and the associated proteins as well as accumulating sufficient energy reserves to complete the task of replicating each chromosome in the nucleus.<\/p>\n<h2>S Phase (Synthesis of DNA)<\/h2>\n<p>Throughout interphase, nuclear DNA remains in a semi-condensed chromatin configuration. In the\u00a0<strong>S phase<\/strong>, DNA replication can proceed through the mechanisms that result in the formation of identical pairs of DNA molecules\u2014sister chromatids\u2014that are firmly attached to the centromeric region. The centrosome is duplicated during the S phase. The two centrosomes will give rise to the <strong>mitotic spindle<\/strong>, the apparatus that orchestrates the movement of chromosomes during mitosis. At the center of each animal cell, the centrosomes of animal cells are associated with a pair of rod-like objects, the <strong>centrioles<\/strong>, which are at right angles to each other. Centrioles help organize cell division. Centrioles are not present in the centrosomes of other eukaryotic species, such as plants and most fungi.<\/p>\n<h2>G<sub>2<\/sub> Phase (Second Gap)<\/h2>\n<p>In the\u00a0<strong>G<sub>2<\/sub> phase<\/strong>, the cell replenishes its energy stores and synthesizes proteins necessary for chromosome manipulation. Some cell organelles are duplicated, and the cytoskeleton is dismantled to provide resources for the mitotic phase. There may be additional cell growth during G<sub>2<\/sub>. The final preparations for the mitotic phase must be completed before the cell is able to enter the first stage of mitosis.<\/p>\n<div class=\"textbox tryit\">\n<h3>Try It<\/h3>\n<p>\t<iframe id=\"assessment_practice_7ea20303-9e11-4ca3-b0f5-4a895cda6cbb\" class=\"resizable\" src=\"https:\/\/assess.lumenlearning.com\/practice\/7ea20303-9e11-4ca3-b0f5-4a895cda6cbb?iframe_resize_id=assessment_practice_id_7ea20303-9e11-4ca3-b0f5-4a895cda6cbb\" frameborder=\"0\" style=\"border:none;width:100%;height:100%;min-height:300px;\"><br \/>\n\t<\/iframe>\n<\/div>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-2387\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Biology 2e. <strong>Provided by<\/strong>: OpenStax. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8\">http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em>. <strong>License Terms<\/strong>: Access for free at https:\/\/openstax.org\/books\/biology-2e\/pages\/1-introduction<\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section>","protected":false},"author":17,"menu_order":6,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Biology 2e\",\"author\":\"\",\"organization\":\"OpenStax\",\"url\":\"http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"Access for free at https:\/\/openstax.org\/books\/biology-2e\/pages\/1-introduction\"}]","CANDELA_OUTCOMES_GUID":"598964f5-fafd-4b8e-80f0-9def8d693c17, 50d5edbd-41e9-447b-826a-3dec4da11793","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-2387","chapter","type-chapter","status-publish","hentry"],"part":205,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapters\/2387","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/wp\/v2\/users\/17"}],"version-history":[{"count":9,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapters\/2387\/revisions"}],"predecessor-version":[{"id":5942,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapters\/2387\/revisions\/5942"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/parts\/205"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapters\/2387\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/wp\/v2\/media?parent=2387"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/pressbooks\/v2\/chapter-type?post=2387"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/wp\/v2\/contributor?post=2387"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology1\/wp-json\/wp\/v2\/license?post=2387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}