{"id":4579,"date":"2017-04-03T20:20:48","date_gmt":"2017-04-03T20:20:48","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/wm-biology2\/?post_type=chapter&#038;p=4579"},"modified":"2024-04-26T01:05:41","modified_gmt":"2024-04-26T01:05:41","slug":"blood-calcium-and-glucose-levels","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/wm-biology2\/chapter\/blood-calcium-and-glucose-levels\/","title":{"raw":"Blood Calcium and Glucose Levels","rendered":"Blood Calcium and Glucose Levels"},"content":{"raw":"<div class=\"textbox learning-objectives\">\r\n<h3>Learning Outcomes<\/h3>\r\n<ul>\r\n \t<li>Explain how different organ systems work together to maintain blood solute levels<\/li>\r\n<\/ul>\r\n<\/div>\r\n<h2>Blood Calcium Levels<\/h2>\r\nAs you have learned, proper calcium levels are important to maintain whole body homeostasis. Calcium ions are used for the heartbeat, the contraction of muscles, the activation of enzymes, and cellular communication. The parathyroid and thyroid glands of the endocrine system detect changes in blood calcium levels. When the parathyroid glands detect low blood calcium levels, several organ systems alter their function to restore blood calcium levels back to normal. The skeletal, urinary, and digestive systems all act as effectors to achieve this goal through negative feedback.\r\n\r\nThe release of parathyroid hormone from the endocrine system triggers osteoclasts of the skeletal system to resorb bone and release calcium into the blood. Similarly, this hormone causes the kidneys of the urinary system to reabsorb calcium and return it to the blood instead of excreting calcium into the urine. Through altered function of the kidneys to form active vitamin D, the small intestine of the digestive system increases the absorption of calcium.\r\n\r\nWhen the thyroid gland detects elevated blood calcium levels, the skeletal, urinary, and digestive systems contribute to lower blood calcium levels back to normal. Release of the hormone calcitonin from the thyroid gland of the endocrine system triggers a series of responses. The osteoblasts of the skeletal system use excess calcium in the blood to deposit new bone. The kidneys of the urinary system excrete excess calcium into the urine instead of reclaiming calcium through reabsorption. Lastly, the kidneys stop forming active vitamin D, which causes decreased intestinal absorption of calcium through the digestive system.\r\n<div class=\"textbox exercises\">\r\n<h3>Practice Question<\/h3>\r\nGraves' disease is an autoimmune disease in which the thyroid is overactive, producing an\u00a0excessive amount of thyroid hormones. Some of the symptoms are heart palpitations and hand tremors.\r\n\r\nWhich system is impacted by the altered calcium levels in Graves' disease, according to the symptoms listed above?\r\n<ol>\r\n \t<li>skeletal<\/li>\r\n \t<li>muscular<\/li>\r\n \t<li>urinary<\/li>\r\n \t<li>digestive<\/li>\r\n<\/ol>\r\n[reveal-answer q=\"114559\"]Show Answer[\/reveal-answer]\r\n[hidden-answer a=\"114559\"]Option b is correct. Skeletal muscles and the heart are impacted by altered calcium levels. The skeletal, urinary, and urinary\u00a0systems are\u00a0involved in calcium homeostasis, but they\u00a0are not involved with the\u00a0symptoms described here.[\/hidden-answer]\r\n\r\n<\/div>\r\n<h2>Blood Glucose\u00a0Levels<\/h2>\r\nThe endocrine functions of the pancreas and liver coordinate efforts to maintain normal blood glucose levels. When pancreatic cells detect low blood glucose levels, the pancreas synthesizes and secretes the hormone glucagon. Glucagon causes the liver to convert the polymerized sugar glycogen into glucose through a process known as glycogenolysis. Glucose then travels through the blood to allow all cells of the body to use it.\r\n\r\nIf pancreatic cells detect high blood glucose levels, the pancreas synthesizes and release the hormone insulin. Insulin causes polymerization of glucose into glycogen, which is then stored in the liver through a process known as glycogenesis.\r\n\r\nThe nervous and digestive systems also play a role in maintaining blood glucose levels. When the stomach is empty and blood glucose levels are low, the digestive system and the brain respond by making you feel hungry\u2014your stomach may \"growl,\" and you may feel pain or discomfort in your midsection. These sensations prompt you to eat, which raises blood glucose levels.\r\n<div class=\"textbox exercises\">\r\n<h3>PRactice Question<\/h3>\r\nThe liver and pancreas are part of both the endocrine system and the digestive system. What is\u00a0the utility of having integrated digestion and regulation?\r\n\r\n[practice-area rows=\"2\"][\/practice-area]\r\n[reveal-answer q=\"641147\"]Show Answer[\/reveal-answer]\r\n[hidden-answer a=\"641147\"]Both the liver and pancreas can sense and help process nutrients to maintain glucose homeostasis. This allows closer regulation.[\/hidden-answer]\r\n\r\n<\/div>\r\n<div class=\"textbox tryit\">\r\n<h3>Try It<\/h3>\r\nhttps:\/\/assess.lumenlearning.com\/practice\/4230efe1-fe68-4733-b697-51826ee2a7ea\r\n<\/div>","rendered":"<div class=\"textbox learning-objectives\">\n<h3>Learning Outcomes<\/h3>\n<ul>\n<li>Explain how different organ systems work together to maintain blood solute levels<\/li>\n<\/ul>\n<\/div>\n<h2>Blood Calcium Levels<\/h2>\n<p>As you have learned, proper calcium levels are important to maintain whole body homeostasis. Calcium ions are used for the heartbeat, the contraction of muscles, the activation of enzymes, and cellular communication. The parathyroid and thyroid glands of the endocrine system detect changes in blood calcium levels. When the parathyroid glands detect low blood calcium levels, several organ systems alter their function to restore blood calcium levels back to normal. The skeletal, urinary, and digestive systems all act as effectors to achieve this goal through negative feedback.<\/p>\n<p>The release of parathyroid hormone from the endocrine system triggers osteoclasts of the skeletal system to resorb bone and release calcium into the blood. Similarly, this hormone causes the kidneys of the urinary system to reabsorb calcium and return it to the blood instead of excreting calcium into the urine. Through altered function of the kidneys to form active vitamin D, the small intestine of the digestive system increases the absorption of calcium.<\/p>\n<p>When the thyroid gland detects elevated blood calcium levels, the skeletal, urinary, and digestive systems contribute to lower blood calcium levels back to normal. Release of the hormone calcitonin from the thyroid gland of the endocrine system triggers a series of responses. The osteoblasts of the skeletal system use excess calcium in the blood to deposit new bone. The kidneys of the urinary system excrete excess calcium into the urine instead of reclaiming calcium through reabsorption. Lastly, the kidneys stop forming active vitamin D, which causes decreased intestinal absorption of calcium through the digestive system.<\/p>\n<div class=\"textbox exercises\">\n<h3>Practice Question<\/h3>\n<p>Graves&#8217; disease is an autoimmune disease in which the thyroid is overactive, producing an\u00a0excessive amount of thyroid hormones. Some of the symptoms are heart palpitations and hand tremors.<\/p>\n<p>Which system is impacted by the altered calcium levels in Graves&#8217; disease, according to the symptoms listed above?<\/p>\n<ol>\n<li>skeletal<\/li>\n<li>muscular<\/li>\n<li>urinary<\/li>\n<li>digestive<\/li>\n<\/ol>\n<div class=\"qa-wrapper\" style=\"display: block\"><span class=\"show-answer collapsed\" style=\"cursor: pointer\" data-target=\"q114559\">Show Answer<\/span><\/p>\n<div id=\"q114559\" class=\"hidden-answer\" style=\"display: none\">Option b is correct. Skeletal muscles and the heart are impacted by altered calcium levels. The skeletal, urinary, and urinary\u00a0systems are\u00a0involved in calcium homeostasis, but they\u00a0are not involved with the\u00a0symptoms described here.<\/div>\n<\/div>\n<\/div>\n<h2>Blood Glucose\u00a0Levels<\/h2>\n<p>The endocrine functions of the pancreas and liver coordinate efforts to maintain normal blood glucose levels. When pancreatic cells detect low blood glucose levels, the pancreas synthesizes and secretes the hormone glucagon. Glucagon causes the liver to convert the polymerized sugar glycogen into glucose through a process known as glycogenolysis. Glucose then travels through the blood to allow all cells of the body to use it.<\/p>\n<p>If pancreatic cells detect high blood glucose levels, the pancreas synthesizes and release the hormone insulin. Insulin causes polymerization of glucose into glycogen, which is then stored in the liver through a process known as glycogenesis.<\/p>\n<p>The nervous and digestive systems also play a role in maintaining blood glucose levels. When the stomach is empty and blood glucose levels are low, the digestive system and the brain respond by making you feel hungry\u2014your stomach may &#8220;growl,&#8221; and you may feel pain or discomfort in your midsection. These sensations prompt you to eat, which raises blood glucose levels.<\/p>\n<div class=\"textbox exercises\">\n<h3>PRactice Question<\/h3>\n<p>The liver and pancreas are part of both the endocrine system and the digestive system. What is\u00a0the utility of having integrated digestion and regulation?<\/p>\n<p><textarea aria-label=\"Your Answer\" rows=\"2\"><\/textarea><\/p>\n<div class=\"qa-wrapper\" style=\"display: block\"><span class=\"show-answer collapsed\" style=\"cursor: pointer\" data-target=\"q641147\">Show Answer<\/span><\/p>\n<div id=\"q641147\" class=\"hidden-answer\" style=\"display: none\">Both the liver and pancreas can sense and help process nutrients to maintain glucose homeostasis. This allows closer regulation.<\/div>\n<\/div>\n<\/div>\n<div class=\"textbox tryit\">\n<h3>Try It<\/h3>\n<p>\t<iframe id=\"assessment_practice_4230efe1-fe68-4733-b697-51826ee2a7ea\" class=\"resizable\" src=\"https:\/\/assess.lumenlearning.com\/practice\/4230efe1-fe68-4733-b697-51826ee2a7ea?iframe_resize_id=assessment_practice_id_4230efe1-fe68-4733-b697-51826ee2a7ea\" frameborder=\"0\" style=\"border:none;width:100%;height:100%;min-height:300px;\"><br \/>\n\t<\/iframe>\n<\/div>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-4579\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Integration of Systems. <strong>Provided by<\/strong>: Open Learning Initiative. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/oli.cmu.edu\/jcourse\/workbook\/activity\/page?context=0baa01e280020ca6005ebffa8138cce4\">https:\/\/oli.cmu.edu\/jcourse\/workbook\/activity\/page?context=0baa01e280020ca6005ebffa8138cce4<\/a>. <strong>Project<\/strong>: Anatomy &amp; Physiology (Open + Free). <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\">CC BY-NC-SA: Attribution-NonCommercial-ShareAlike<\/a><\/em><\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section>","protected":false},"author":17,"menu_order":5,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Integration of Systems\",\"author\":\"\",\"organization\":\"Open Learning Initiative\",\"url\":\"https:\/\/oli.cmu.edu\/jcourse\/workbook\/activity\/page?context=0baa01e280020ca6005ebffa8138cce4\",\"project\":\"Anatomy & Physiology (Open + Free)\",\"license\":\"cc-by-nc-sa\",\"license_terms\":\"\"}]","CANDELA_OUTCOMES_GUID":"6bd5451f-66dc-452e-a0bb-b0e999409b7a, 93f8215a-f304-40b8-8e4b-4d05c6ce0b9c","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-4579","chapter","type-chapter","status-publish","hentry"],"part":149,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/4579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/users\/17"}],"version-history":[{"count":6,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/4579\/revisions"}],"predecessor-version":[{"id":8485,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/4579\/revisions\/8485"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/parts\/149"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/4579\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/media?parent=4579"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapter-type?post=4579"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/contributor?post=4579"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/license?post=4579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}