{"id":635,"date":"2015-04-20T15:54:57","date_gmt":"2015-04-20T15:54:57","guid":{"rendered":"https:\/\/courses.candelalearning.com\/biology2xmaster\/?post_type=chapter&#038;p=635"},"modified":"2024-04-26T02:32:30","modified_gmt":"2024-04-26T02:32:30","slug":"putting-it-together-the-immune-system","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/wm-biology2\/chapter\/putting-it-together-the-immune-system\/","title":{"raw":"Putting It Together: The Immune System","rendered":"Putting It Together: The Immune System"},"content":{"raw":"This video tells us about the team of deadly ninja assassins that is tasked with protecting our bodies from all the bad guys that want to kill us\u2014also known as our immune system.\r\n\r\nhttps:\/\/youtu.be\/CeVtPDjJBPU\r\n<h2>Autoimmune Diseases<\/h2>\r\n<p id=\"fs-id1167663662015\">Although the immune system protects the body by attacking invading \u201cenemies\u201d (pathogens), in some cases, the immune system can mistakenly identify the body\u2019s own cells as the enemy, resulting in <span data-type=\"term\">autoimmune disease<\/span>.<\/p>\r\n<p id=\"fs-id1167663628667\">Autoimmune diseases are those in which the body is attacked by its own specific adaptive immune response. In normal, healthy states, the immune system induces <span data-type=\"term\">tolerance<\/span>, which is a lack of an anti-self immune response. However, with autoimmunity, there is a loss of immune tolerance. Autoimmune diseases can have a variety of mixed symptoms that flare up and disappear, making diagnosis difficult.<\/p>\r\n<p id=\"fs-id1167661368356\">The following are all examples of autoimmune diseases:<\/p>\r\n\r\n<ul>\r\n \t<li>celiac disease<\/li>\r\n \t<li>hyperthyroidism<\/li>\r\n \t<li>Type 1 Diabetes<\/li>\r\n \t<li>multiple sclerosis<\/li>\r\n \t<li>rheumatoid arthritis<\/li>\r\n \t<li>lupus<\/li>\r\n<\/ul>\r\nThe causes of autoimmune disease are a combination of the individual's genetic makeup and the effect of environmental influences, such as sunlight, infections, medications, and environmental chemicals. However, the vagueness of this list reflects our poor understanding of the etiology of these diseases. Except in a very few specific diseases, the initiation event(s) of most autoimmune states has not been fully characterized.\r\n<h2>Flashcards<\/h2>\r\n<div id=\"post-3888\" class=\"standard post-3888 chapter type-chapter status-publish hentry\">\r\n<div class=\"entry-content\">\r\n\r\nIt is tempting to view different topics as completely separate, but in fact the ideas we cover in this course are often connected to one another. If you don\u2019t retain the vocabulary from module to module, those connections can be missed. As you continue on, remember to come back and review the terms you\u2019ve learned in order to increase your depth of knowledge.\r\n\r\n<iframe src=\"https:\/\/lumenlearning.h5p.com\/content\/1291177324646748268\/embed\" width=\"1088\" height=\"637\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" data-mce-fragment=\"1\"><\/iframe>\r\n\r\n<\/div>\r\n<\/div>","rendered":"<p>This video tells us about the team of deadly ninja assassins that is tasked with protecting our bodies from all the bad guys that want to kill us\u2014also known as our immune system.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-1\" title=\"Your Immune System: Natural Born Killer - Crash Course Biology #32\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/CeVtPDjJBPU?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<h2>Autoimmune Diseases<\/h2>\n<p id=\"fs-id1167663662015\">Although the immune system protects the body by attacking invading \u201cenemies\u201d (pathogens), in some cases, the immune system can mistakenly identify the body\u2019s own cells as the enemy, resulting in <span data-type=\"term\">autoimmune disease<\/span>.<\/p>\n<p id=\"fs-id1167663628667\">Autoimmune diseases are those in which the body is attacked by its own specific adaptive immune response. In normal, healthy states, the immune system induces <span data-type=\"term\">tolerance<\/span>, which is a lack of an anti-self immune response. However, with autoimmunity, there is a loss of immune tolerance. Autoimmune diseases can have a variety of mixed symptoms that flare up and disappear, making diagnosis difficult.<\/p>\n<p id=\"fs-id1167661368356\">The following are all examples of autoimmune diseases:<\/p>\n<ul>\n<li>celiac disease<\/li>\n<li>hyperthyroidism<\/li>\n<li>Type 1 Diabetes<\/li>\n<li>multiple sclerosis<\/li>\n<li>rheumatoid arthritis<\/li>\n<li>lupus<\/li>\n<\/ul>\n<p>The causes of autoimmune disease are a combination of the individual&#8217;s genetic makeup and the effect of environmental influences, such as sunlight, infections, medications, and environmental chemicals. However, the vagueness of this list reflects our poor understanding of the etiology of these diseases. Except in a very few specific diseases, the initiation event(s) of most autoimmune states has not been fully characterized.<\/p>\n<h2>Flashcards<\/h2>\n<div id=\"post-3888\" class=\"standard post-3888 chapter type-chapter status-publish hentry\">\n<div class=\"entry-content\">\n<p>It is tempting to view different topics as completely separate, but in fact the ideas we cover in this course are often connected to one another. If you don\u2019t retain the vocabulary from module to module, those connections can be missed. As you continue on, remember to come back and review the terms you\u2019ve learned in order to increase your depth of knowledge.<\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/lumenlearning.h5p.com\/content\/1291177324646748268\/embed\" width=\"1088\" height=\"637\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" data-mce-fragment=\"1\"><\/iframe><\/p>\n<\/div>\n<\/div>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-635\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Microbiology. <strong>Provided by<\/strong>: OpenStax. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"http:\/\/cnx.org\/contents\/e42bd376-624b-4c0f-972f-e0c57998e765@4.7\">http:\/\/cnx.org\/contents\/e42bd376-624b-4c0f-972f-e0c57998e765@4.7<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em>. <strong>License Terms<\/strong>: Download for free at http:\/\/cnx.org\/contents\/e42bd376-624b-4c0f-972f-e0c57998e765@4.7<\/li><\/ul><div class=\"license-attribution-dropdown-subheading\">All rights reserved content<\/div><ul class=\"citation-list\"><li>Your Immune System: Natural Born Killer - Crash Course Biology #32. <strong>Authored by<\/strong>: CrashCourse. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"https:\/\/youtu.be\/CeVtPDjJBPU\">https:\/\/youtu.be\/CeVtPDjJBPU<\/a>. <strong>License<\/strong>: <em>All Rights Reserved<\/em>. <strong>License Terms<\/strong>: Standard YouTube license<\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section>","protected":false},"author":17,"menu_order":18,"template":"","meta":{"_candela_citation":"[{\"type\":\"copyrighted_video\",\"description\":\"Your Immune System: Natural Born Killer - Crash Course Biology #32\",\"author\":\"CrashCourse\",\"organization\":\"\",\"url\":\"https:\/\/youtu.be\/CeVtPDjJBPU\",\"project\":\"\",\"license\":\"arr\",\"license_terms\":\"Standard YouTube license\"},{\"type\":\"cc\",\"description\":\"Microbiology\",\"author\":\"\",\"organization\":\"OpenStax\",\"url\":\"http:\/\/cnx.org\/contents\/e42bd376-624b-4c0f-972f-e0c57998e765@4.7\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"Download for free at http:\/\/cnx.org\/contents\/e42bd376-624b-4c0f-972f-e0c57998e765@4.7\"}]","CANDELA_OUTCOMES_GUID":"1bbbce99-39d0-477b-9b5f-9d493eccc7cf","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-635","chapter","type-chapter","status-publish","hentry"],"part":4294,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/635","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/users\/17"}],"version-history":[{"count":11,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/635\/revisions"}],"predecessor-version":[{"id":8653,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/635\/revisions\/8653"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/parts\/4294"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapters\/635\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/media?parent=635"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/pressbooks\/v2\/chapter-type?post=635"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/contributor?post=635"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-biology2\/wp-json\/wp\/v2\/license?post=635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}