{"id":3274,"date":"2016-11-02T20:43:13","date_gmt":"2016-11-02T20:43:13","guid":{"rendered":"https:\/\/courses.lumenlearning.com\/wm-biology1\/?post_type=chapter&#038;p=3274"},"modified":"2024-04-26T00:24:06","modified_gmt":"2024-04-26T00:24:06","slug":"outcome-prokaryotic-gene-regulation","status":"publish","type":"chapter","link":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/chapter\/outcome-prokaryotic-gene-regulation\/","title":{"raw":"Introduction to Prokaryotic Gene Regulation","rendered":"Introduction to Prokaryotic Gene Regulation"},"content":{"raw":"<h2>What you'll learn to do: Understand the basic steps in gene regulation in prokaryotic cells<\/h2>\r\nThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function are encoded together in blocks called <strong>operons<\/strong>. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.\r\n\r\nIn prokaryotic cells, there are three types of regulatory molecules that can affect the expression of operons: repressors, activators, and inducers. <strong>Repressors<\/strong> are proteins that suppress transcription of a gene in response to an external stimulus, whereas <strong>activators<\/strong> are proteins that increase the transcription of a gene in response to an external stimulus. Finally, <strong>inducers<\/strong> are small molecules that either activate or repress transcription depending on the needs of the cell and the availability of substrate.","rendered":"<h2>What you&#8217;ll learn to do: Understand the basic steps in gene regulation in prokaryotic cells<\/h2>\n<p>The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function are encoded together in blocks called <strong>operons<\/strong>. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.<\/p>\n<p>In prokaryotic cells, there are three types of regulatory molecules that can affect the expression of operons: repressors, activators, and inducers. <strong>Repressors<\/strong> are proteins that suppress transcription of a gene in response to an external stimulus, whereas <strong>activators<\/strong> are proteins that increase the transcription of a gene in response to an external stimulus. Finally, <strong>inducers<\/strong> are small molecules that either activate or repress transcription depending on the needs of the cell and the availability of substrate.<\/p>\n\n\t\t\t <section class=\"citations-section\" role=\"contentinfo\">\n\t\t\t <h3>Candela Citations<\/h3>\n\t\t\t\t\t <div>\n\t\t\t\t\t\t <div id=\"citation-list-3274\">\n\t\t\t\t\t\t\t <div class=\"licensing\"><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Original<\/div><ul class=\"citation-list\"><li>Outcome: Prokaryotic Gene Regulation. <strong>Provided by<\/strong>: Lumen Learning. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em><\/li><\/ul><div class=\"license-attribution-dropdown-subheading\">CC licensed content, Shared previously<\/div><ul class=\"citation-list\"><li>Biology. <strong>Provided by<\/strong>: OpenStax CNX. <strong>Located at<\/strong>: <a target=\"_blank\" href=\"http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8\">http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8<\/a>. <strong>License<\/strong>: <em><a target=\"_blank\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY: Attribution<\/a><\/em>. <strong>License Terms<\/strong>: Download for free at http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8<\/li><\/ul><\/div>\n\t\t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t <\/section>","protected":false},"author":17,"menu_order":5,"template":"","meta":{"_candela_citation":"[{\"type\":\"original\",\"description\":\"Outcome: Prokaryotic Gene Regulation\",\"author\":\"\",\"organization\":\"Lumen Learning\",\"url\":\"\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"cc\",\"description\":\"Biology\",\"author\":\"\",\"organization\":\"OpenStax CNX\",\"url\":\"http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"Download for free at http:\/\/cnx.org\/contents\/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8\"}]","CANDELA_OUTCOMES_GUID":"3d5fa144-93ad-4b87-a30b-ec7c4ff31b90","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-3274","chapter","type-chapter","status-publish","hentry"],"part":3270,"_links":{"self":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapters\/3274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/wp\/v2\/users\/17"}],"version-history":[{"count":14,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapters\/3274\/revisions"}],"predecessor-version":[{"id":5317,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapters\/3274\/revisions\/5317"}],"part":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/parts\/3270"}],"metadata":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapters\/3274\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/wp\/v2\/media?parent=3274"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/pressbooks\/v2\/chapter-type?post=3274"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/wp\/v2\/contributor?post=3274"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/courses.lumenlearning.com\/wm-nmbiology1\/wp-json\/wp\/v2\/license?post=3274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}